To open a pdf file you will need compatible software such as adobe reader. Laugierhunziker syndrome genetic and rare diseases. For language access assistance, contact the ncats public information officer. A read is counted each time someone views a publication summary such as the title, abstract, and list of authors, clicks on a figure, or views or downloads the fulltext. Hyperpigmentation mimicking laugier syndrome, levodopa.
Laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules 15 mm in size, frequently associated with longitudinal melanonychia. The hyperpigmentation presented in laugierhunziker syndrome is benign and should be differentiated from peutzjeghers syndrome. Additional conjunc tival and penile pigmentation in laugierhunziker syndrome. Laugier hunziker syndrome is an idiopathic, acquired, benign, melanotic hyperpigmentation of the lips and oral mucosa, which is often associated with a longitudinal pigmentation of the nails. Extended mucocutaneous features have been observed since that original description, including macular pigmentation of the genitalia. Abstract laugierhunziker syndrome is a rare benign acquired disorder of unknown pathogenesis, firstly described in 1970, characterized by macular mucocutaneous hyperpigmentation frequently associated with longitudinal melanonychia.
Laugierhunziker syndrome lhs is a rare, benign and acquired disorder characterized by hyperpigmentation of the oral cavity and lips along with longitudinal. First, laugier hunziker syndrome lesions are progressively acquired in young or middleage adults, profusion of periori. These files will have pdf in brackets along with the filesize of the download. Feb 27, 2019 please use one of the following formats to cite this article in your essay, paper or report. Jun 27, 2019 extended mucocutaneous pigmentation has become a recognized feature of laugier hunziker syndrome. If you continue browsing the site, you agree to the use of cookies on this website. Laugierhunziker syndrome is considered to be a benign disease with no systemic manifestation or malignant potential.
Laugierhunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugierhunziker syndrome is a cutaneous condition characterized by hyperpigmentation of the oral mucosa, longitudinal melanonychia, and genital melanosis. Laugier hunziker syndrome lhs is a rare acquired benign macular hyperpigmentation of the lips and oral mucosa which is often associated with longitudinal melanonychia. Laugierhunziker syndrome is an idiopathic, acquired, benign, melanotic hyperpigmentation of the lips and oral mucosa, which is often associated with a longitudinal pigmentation of the nails. Laugierhunziker syndrome in endocrine clinical practice in. Pdf most of the documents on the racgp website are in portable document format pdf. Laugierhunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia in adults. If you do not have it you can download adobe reader free of charge. Pdf laugierhunziker syndrome is a rare acquired disorder characterized by diffuse hyperpigmentation of the oral mucosa and longitudinal melanonychia. Melanotic macular hyperpigmentation has been observed on the neck, the thorax, the abdomen, the dorsal and lateral aspects of the fingers, the palms and soles, the genitalia, the perineum, the perianal skin, and the anal mucosa of patients with laugier hunziker syndrome.
Perez elizondo a, del pino rojas g, lopez salgado ml. Malattia di laugier hunziker ildermatologorisponde. Laugierhunziker syndrome lhs is an acquired, benign pigmentary skin condition involving oral cavity including lower lip in the form of brown black macules. Peutzjeghers syndrome and management recommendations. Melanotic macular hyperpigmentation has been observed on the neck, the thorax, the abdomen, the dorsal and lateral aspects of the fingers, the palms and soles, the genitalia, the perineum, the perianal skin, and the anal mucosa of patients with laugierhunziker syndrome. The syndrome must be included in the differential diagnosis of diffuse oral pigmentation to exclude other conditions with systemic implications. Pigmentazioni alle mucose genitale o orale dermatologo a lucca. Laugier hunziker syndrome is a rare, acquired disorder characterized by lenticular hyperpigmentation of the oral mucosa and longitudinal melanonychia. Laugier hunziker syndrome is a rare disorder that is characterized by adultonset hyperpigmented macules of the lips, oral cavity, and fingertips.
We describe a 43yearold white woman with the clinical and histological features of laugierhunziker. Laugierhunziker syndrome lhs was initially described in 1970 as acquired, benign hyperpigmented macules of the lips and buccal mucosa frequently associated with longitudinal melanonychia. We describe a 43yearold white woman with the clinical and histological features of laugier hunziker. Longitudinal melanonychia is present in the majority of cases. May 01, 2003 hyperpigmentation mimicking laugier syndrome, levodopa therapy and addisons disease hyperpigmentation mimicking laugier syndrome, levodopa therapy and addisons disease vega gutierrez, j. Read oral manifestations of idiopathic lenticular mucocutaneous pigmentation laugier. Please use one of the following formats to cite this article in your essay, paper or report. Summary laugier hunziker syndrome is an infrequent benign and acquired condition of the lips, oral mucosa and nails. Extended mucocutaneous pigmentation has become a recognized feature of laugierhunziker syndrome. A diagnosis of the laugierhunziker syndrome lhs was made.
Ayoub n, barete s, bouaziz jd, le pelletier f, frances c. If you have problems viewing pdf files, download the latest version of adobe reader. We present the case of a 63yearold female with progressive, asymptomatic hyperpigmentation of buccal mucosa and a 7year history of hyperpigmentation in several fingernails. Medicine, dermatology, diagnosis, laugierhunziker syndrome, hyperpigmentation, skin, differential diagnosis.